Please find an overview of all relevant terms and corresponding explanations. If your term is not included or you have any question, please contact us. We are happy to help.
Antibodies
Protein molecules whose specific function is to defend the body from pathogens; synonym: immunoglobulins
Apheresis
Procedure by which different blood components are separated from each other
ARTICE
Registered trademark of the Immune competence enhancement technology of ARTCLINE, former known as EISS.
BfArM
Bundesinstitut für Arzneimittel und Medizinprodukte (German Federal Institute for Pharmaceuticals and Medical Devices)
Bio-hybrid
Combination of a mechanical and a biological system
Bioreactor
Device that ensures the ability of a biological system (e.g. cells or bacteria) to function by stabilising the temperature, oxygen and nutrition
Biosensor
Procedure or device that carries out a test based on the reaction of a biological system
Blood cells
Red blood cells transport oxygen in the blood; white blood cells detect and defend against incoming pathogens.
Blood plasma
All blood components that are not cells, also referred to as “blood water”, contains proteins, fats etc.
Causal
Be the cause for
Chemiluminescence
Release of light as the result of a chemical reaction
Contamination
Impurities
CPMP
Committee for Proprietary Medicinal Products: advisory committee for the EMEA for Pharmaceuticals
Cryoconservation
Storage in a frozen state
Cytokines
Protein mediators released by cells that regulate the function of other cells
Diagnostics
All activities dedicated to detecting past, present and future illnesses
EMEA
European Medicines Agency: European regulatory body for the centralised marketing approval of pharmaceuticals within the European Union
Endotoxins
Membrane components of some bacteria that induce fever
Enzymes
Bio-catalysers based on proteins
Extracorporeal
Something that takes place outside the body
FDA
U.S. Food and Drug Administration: regulatory body for the marketing approval of pharmaceuticals, medical products, food, cosmetics within the U.S.
Fluorometer
Device for measuring fluorescence
Fluorescence
Light of a different wavelength released after illumination
GMP
Good Manufacturing Practice: All of the regulations on the correct manufacture of pharmaceuticals
Granulocytes
Small blood phagocytes, make up around 50% of white blood cells
HLA
Human Leukocyte Antigen: Individual-specific protein molecules in cells by which the immune system recognises whether they are the body’s own cells
Human albumin
Albumin is the main protein in blood plasma
IDE
Investigational Device Exemption: allowance for using new medical devices in clinical studies
Idiopathic
With no detectable cause
Immune system
All of an organism’s defence mechanisms against the pathogens
Immunoglobulin
See Antibodies
Immunomodulation
Influencing the immune system
In-vitro
Outside the organism, e.g. in a test-tube
In-vivo
In a living organism
i.v.
“Intravenous”: to inject something into a blood vein
KfW
Kreditanstalt für Wiederaufbau (“Credit Institute for Reconstruction”, i.e. German Institution to grant governmental support)
Lethality
Proportion of those who died of those who were sick
Leukocytes
White blood cells
Macrophages
Large phagocytes
Mediators
Messengers, substances that transfer signals
Monocytes
Subset of large phagocytes
Mortality
Proportion of the population (group) who died
PEI
Paul-Ehrlich-Institute: Regulatory body for the marketing approval of some pharmaceuticals (blood, biotech, vaccines) within Germany
Phagocytes
Immune cells that take up and kill bacteria and fungi
Phagocytosis
The process of taking up bacteria or fungi
Plasma
See blood plasma
Plasmapheresis
Procedure in which blood plasma is separated from blood cells
PMA
Pre-Market-Approval: Approval procedure for innovative medical products in the USA
Prognosis
Forecast of how something will turn out
Prospective
Looking to the future
Protein
Protein molecule
Reimbursement
Repayment of costs (e.g. by health insurance company)
Rheumatism
Actually “rheumatoid arthritis”, covers joint and endocardium inflammations
Serum
All soluble blood plasma components after coagulation. Is the same as blood plasma without the coagulation factors
SIRS
Septic Inflammatory Response Syndrome: The patient has the clinical symptoms of a sepsis but at that particular point in time there is no evidence for an infection (yet). Frequently becomes sepsis.
Therapy
Treating an illness
Thrombocytopenia
Depletion of platelets, results in heavier bleeding
Tissue engineering
In-vitro production of tissues and organs
510(k)
Approvals procedure for medical devices in the USA that have substantial equivalence to a medical device that has already been approved