Practical experience is demonstrating proof

In 1998 the concept of immune cell based extracorporeal therapy was first introduced and subsequently tested in rat and pig animal models.

Both models showed a survival benefit for the extracorporeally treated animals. Subsequently, a “first in man” phase I/II clinical trial was started. Ten patients with septic shock were treated twice within three days.

The results of this clinical trial have been published:
http://www.ncbi.nlm.nih.gov/pubmed/21371308

“First in man” study
“First in man” study